The Simplest Wedding

The groom had been in a coma for almost a year. The bride was, the guests speculated, a feral spirit. And, yet, everything had gone according to the accepted practices of this day and age

Reflecting on the Use of Photo-elicitation Methods in IPA Research. Enhancing the Interpretative Lens and Re-balancing Power Back to the Participant. A Review of Published Studies

The use of visual and creative methods, specifically photo-elicitation in qualitative research has seen an increase in popularity in applied social science research, particularly in studies of psychology. This paper considers the evolution of the photograph as a research tool, particularly when combined with one-to-one interviewing. This paper situates the use of the photograph within historical and disciplinary contexts whilst offering new perspectives on its application to psychological fields of study. We argue that there are interesting benefits associated with supplementing qualitative methods such as one-to-one interviews with photographic stimuli. We present a recent systematic review of photo-elicitation used in research which identifies as being informed by Interpretative Phenomenological Analysis (IPA). Interpretative phenomenological Analysis is a particular qualitative approach which aims produce an account of lived experience. It is often unconcerned by adhering to the application of pre-existing theoretical preconceptions and instead offers an inductive, iterative and highly idiographic account of a phenomena of which the participant has direct experience of. This may be phenomena linked to personal changes in health and illness, or even adapting to new learning environments. Central to the purpose of IPA is the recognition that this account of lived experience is an interpretative endeavor between both participant and analyst. We argue that this need for interpretation and co-construction offers space for creative methods to ‘bridge the gap’ between simply describing a phenomena and entering into the symbolic, metaphorical interpretative world of meaning making which pushes IPA research from mediocrity to excellence. In this review we aimed to capture information related to the use of photographic methods in IPA research with particular interest in exploring the body of published work across the following protocols; 1) sample for inclusion, 2) domain of study, 3) orientation of research questions, 4) design features, 5) variation of photo-method, 6) outcomes of research and 7) critical appraisal of study. There are 14 published articles utilising photographs in IPA from 2010-2018. These studies were conducted internationally and reach across different topic domains including health, developmental, education and occupational research. The reviewed studies extend across the age span and there was notable younger age participants involved. Using photographs offered particular advantages in comparison to interview alone. These include; (a) to empower marginalized, ‘hard to reach’ groups (b) to facilitate in-depth interpretative discussions of abstract, ‘metaphorical’ concepts, sensitive issues (c) to synthesise data with other methods to strengthen and d) enhance trustworthiness of findings. There was considerable variation in how photographs were ‘produced’ ranging from photos, ‘elicited’ by participants or as a secondary artefact produced by researcher as a stimulus for discussion. Visual methods using photographs vary, and include photo-narratives, photo-journals, photo-montage, photo-questionnaires. We situation our review within fast moving changes and opportunities for this method within a wider ‘open science’ framework and also pay particular attention to exploring ethical issues to ensure confidentiality, consent, privacy and wider 2018 General Data Protection Regulation adherence

Weekend Effect Pada Indeks Harga Saham Gabungan (Ihsg) Indonesia Pasca Krisis

Weekend effect is a form of inefficiency that makes stock returns are not random (predictable) and repetitive which is against the efficient market theory by Fama (1991). This study aims to encourage stock investor knowledge about these anomalies, and act more measurably, so that a more efficient market can be achieved. This study uses a regression method that is looking for a significant value between days against the daily return index with the aim of finding a trading pattern on a particular day, especially on Monday and Friday. As a result, the weekend effect occurs during the post-crisis impact on the real sector, in other words affect the performance of the company's stock returns as a whole so that the global financial crisis that is post-crisis 2007-2008 has a negative statement on the weekend effect.Keywords: weekend effect; post crisis; return; efficient market; anomaly marke

Weekend Effect Pada Indeks Harga Saham Gabungan (Ihsg) Indonesia Pasca Krisis

Weekend effect is a form of inefficiency that makes stock returns are not random (predictable) and repetitive which is against the efficient market theory by Fama (1991). This study aims to encourage stock investor knowledge about these anomalies, and act more measurably, so that a more efficient market can be achieved. This study uses a regression method that is looking for a significant value between days against the daily return index with the aim of finding a trading pattern on a particular day, especially on Monday and Friday. As a result, the weekend effect occurs during the post-crisis impact on the real sector, in other words affect the performance of the company's stock returns as a whole so that the global financial crisis that is post-crisis 2007-2008 has a negative statement on the weekend effect.Keywords: weekend effect; post crisis; return; efficient market; anomaly marke

Modeling and Extraction of Transport Parameters to Simulate Drug Delivery in the Murine Cochlea

The usage of 1D and 3D models to simulate drug transport through the inner ear is a prominent method in cochlear fluid pharmacokinetics. However, the data used to create these models, is often based on invasive sampling methods that limit the spatial resolution given the size of the cochlear compartments within which solute can be measured. In this work by leveraging 3-D registered micro-Computed Tomography (μCT) scans of the murine cochlea that have been taken as iodinated contrast agent is delivered to it, we extract transport parameters and simulate a forward 1D model that allows variable and pulsatile delivery profiles over time and can be extended to the use of other drugs. Our 1D model may be used to simulate transport of a compound within the primary scalae or compartments of the cochlea namely: scala tympani (ST), scala vestibuli (SV) and scala media (SM). We investigate extracting transport parameters of the 1D model for the iodinated contrast agent (Iopamidol), such as the concentration dependent diffusion coefficient, along with permeabilities across membranes that represent transfer between the primary scalae and clearance out to blood. Flow rates that change over time are also learned, to account for leakage due to experimental set up. Dimensions of cochlear structures considered in the model, and empirical concentration profiles are extracted non-invasively over regional cross sections of a set of registered μCT scans of the mouse cochlea while an Iodinated contrast agent (Iopamidol) is delivered to it. Given initial estimates of the transport parameters, we use a simple iterative gradient descent approach to minimize the mean-squared error between our predicted concentrations from the 1D model and those derived empirically. We put forth a method to illustrate that once these parameters are learned for the contrast agent, they can be adjusted to simulate the delivery of other compounds, and can also be used to study various infusion paradigms to maintain a suitable therapeutic window for optimal, effective and safe administration of a drug. The results are important in the development of such paradigms for the prevention and treatment of acute and chronic types of hearing loss